{"id":13898,"date":"2022-12-07T06:05:22","date_gmt":"2022-12-07T12:05:22","guid":{"rendered":"https:\/\/www.ulprospector.com\/knowledge\/?p=13898"},"modified":"2023-04-26T13:45:00","modified_gmt":"2023-04-26T19:45:00","slug":"fb-collagen-benefits-types-and-market","status":"publish","type":"post","link":"https:\/\/ulprospector.ul.com\/13898\/fb-collagen-benefits-types-and-market\/","title":{"rendered":"Collagen: Benefits, Types, and Market"},"content":{"rendered":"<p><a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=Collagen&amp;sug=1&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-13901\" src=\"https:\/\/ulprospector.ul.com\/media\/2022\/11\/GettyImages-508166493-chocolate-whey-HEADER-600x400-1.jpg\" alt=\"Chocolate whey powder\" width=\"600\" height=\"400\" srcset=\"https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2022\/11\/GettyImages-508166493-chocolate-whey-HEADER-600x400-1.jpg 600w, https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2022\/11\/GettyImages-508166493-chocolate-whey-HEADER-600x400-1-300x200.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/>Collagen<\/a> is the most abundant protein in the human body, serving as the main structural protein of skin, tendons, ligaments, and bones.<\/p>\n<p>Although <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Products\/17323\/Milk-Proteins\/search?k=milk+based+proteins&amp;st=31&amp;so=k_0+pt_17294&amp;sl=145171711&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">milk-based protein<\/a>, specifically <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Products\/17332\/Whey-Proteins\/Product\/search?k=milk+based+proteins&amp;st=31&amp;so=k_0+pt_17332&amp;sl=145171711&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">whey<\/a>, dominates the global protein market, in part because it is inexpensive to manufacture compared with other protein sources and offers high bioavailability, collagen supplements are increasing in popularity.<\/p>\n<p>This article provides an overview on the benefits, types, and market of collagen.<\/p>\n<h2>Collagen types<\/h2>\n<p>Collagen is a structural protein composed primarily of <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=glycine&amp;st=31&amp;so=k_0&amp;sl=145171885&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">glycine<\/a>, proline, and hydroxyproline.\u00a0The primary amino acid sequence of collagen is glycine-proline-X or glycine-X-hydroxyproline.\u00a0X represents any of the other 17 amino acids.<\/p>\n<h3>There are four structural levels of <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=Collagen&amp;sug=1&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">collagen<\/a>:<\/h3>\n<ul>\n<li>Primary (amino acid triplet)<\/li>\n<li>Secondary (the \u03b1-helix)<\/li>\n<li>Tertiary structure (triple helix)<\/li>\n<li>Quaternary structure (fibrils)<\/li>\n<\/ul>\n<p>The structures collagen form determines its type.\u00a0There are 28 types of <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=Collagen&amp;sug=1&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">collagen<\/a>, but by far, the most common are types I through V, with type 1 comprising over 90% of the collagen in the human body.\u00a0Here\u2019s a look at the five most common types of <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=Collagen&amp;sug=1&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">collagen<\/a>, their application, and the tissue or organ in which they are present.<\/p>\n<table>\n<tbody>\n<tr>\n<td><strong>Collagen<\/strong><\/td>\n<td><strong>Function or Application<\/strong><\/td>\n<td><strong>Tissue or Organ<\/strong><\/td>\n<\/tr>\n<tr>\n<td>Type I<\/td>\n<td>Cell-bone matrix, bone regeneration<\/td>\n<td>Skin, bone, teeth, tendons, ligament, vascular ligature<\/td>\n<\/tr>\n<tr>\n<td>Type II<\/td>\n<td>Cartilage repair, arthritis treatment<\/td>\n<td>Cartilage<\/td>\n<\/tr>\n<tr>\n<td>Type lll<\/td>\n<td>Reticular fibers (supporting mesh of soft tissues)<\/td>\n<td>Muscle, blood vessels<\/td>\n<\/tr>\n<tr>\n<td>Type IV<\/td>\n<td>Basal lamina component, cell attachment surface treatment, marker of nephropathy<\/td>\n<td>Basal lamina<\/td>\n<\/tr>\n<tr>\n<td>Type V<\/td>\n<td>Corneal regeneration treatment<\/td>\n<td>Hair, cell surfaces, placenta<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>Table 1 adapted from Wang H<sup>1<\/sup><\/p>\n<p><a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=Collagen&amp;sug=1&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">Collagen<\/a> can be extracted from natural animal and plant sources or be obtained from protein production systems using bacteria, yeast, insects, mammalian cells, or artificial fibrils.<sup>1 <\/sup>The most common animal collagen sources include <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/search?k=bovine+collagen&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">bovine<\/a> (cow), <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=porcine+collagen&amp;st=31&amp;so=k_0&amp;sl=145172793&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">porcine<\/a> (pig), and <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=marine+collagen&amp;st=31&amp;so=k_0&amp;sl=145173151&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">marine<\/a> organisms.<\/p>\n<p>A hydrolysis extraction process can be used, depending on the origin of the raw materials. <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/search?k=Hydrolyzed+Collagen&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">Hydrolyzed collagen<\/a> (collagen peptides) has a higher solubility in water compared with native collagen and is generally more bioavailable.<\/p>\n<p>Collagen types I, II, and III are most commonly used for dietary supplements and cosmetics. Type I is mainly derived from marine collagen, type ll from chicken and bovine collagen, and type lll from porcine and bovine collagen.<\/p>\n<p>These supplements may offer therapeutic benefits for<sup>1<\/sup>:<\/p>\n<ul>\n<li>bone health<\/li>\n<li>muscle function and strength<\/li>\n<li>wound healing<\/li>\n<li>joint health<\/li>\n<li>skin aging<\/li>\n<\/ul>\n<p>Other promising research suggests collagen treatments like injections and medical and dental scaffolds may be useful for managing bone defects, gastroesophageal reflux (GERD), and periodontal disease.<\/p>\n<h2>Collagen market<\/h2>\n<p>According to a 2021 analysis by Grand View Research, the global <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=Collagen&amp;sug=1&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">collagen<\/a> market is expected to grow at a compounded annual growth rate of 5.5% over the next seven years to reach $2.88 billion by 2028.\u00a0Driving this growth is an increase in consumers\u2019 knowledge and awareness surrounding collagen\u2019s benefits, especially as they relate to healthy aging.<\/p>\n<p>Pills and gummies accounted for more than half of the global market revenue in 2021; however, collagen powder is expected to experience the highest growth through 2028 according to the analysis.<\/p>\n<p><a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/search?k=bovine+collagen&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">Bovine-derived collagen<\/a> is likely to exhibit major growth, owing to its therapeutic role for joint and skin health. Though, depending on the source from which its derived, some people may have sensitivities or allergies to collagen supplements.<\/p>\n<p>An increased adoption of vegetarian diets are expected to limit market growth.\u00a0As an alternative, some brands offer products known as collagen builders or boosters.<\/p>\n<p>Collagen builders don\u2019t contain collagen but contain building blocks for collagen production such as biotin and vitamin C, other cartilage forming-molecules like <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=Hyaluronic+Acid&amp;sug=1&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">hyaluronic acid<\/a>, and plant-based ingredients rich in the amino acids necessary for its synthesis.<\/p>\n<h3>The bottom line<\/h3>\n<p>Collagen is the body\u2019s most abundant protein and provides structure to hair, skin, nails, ligaments, tendons, and bones.\u00a0Of the 28 types of collagen, types I through V are the most abundant in the body, with type I comprising 90% of the body\u2019s collagen.<\/p>\n<p>Collagen supplements originate from various sources, including <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=porcine+collagen&amp;st=31&amp;so=k_0&amp;sl=145172793&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">porcine<\/a>, <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/search?k=bovine+collagen&amp;st=31&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">bovine<\/a>, and <a href=\"https:\/\/www.ulprospector.com\/en\/na\/Food\/Product\/search?k=marine+collagen&amp;st=31&amp;so=k_0&amp;sl=145173151&amp;utm_source=KnowledgeCenter&amp;utm_medium=article&amp;utm_campaign=Collagen&amp;utm_term=2022FB&amp;utm_content=Gavin\" target=\"_blank\" rel=\"noopener\">marine<\/a>, and may offer therapeutic benefits for various conditions and health goals.<\/p>\n<p>The global market for collagen supplements is expected to stay strong in the coming years, driven by consumers seeking targeted health solutions, especially in relation to healthy aging.<\/p>\n<p><strong>References<\/strong><\/p>\n<ol>\n<li>Wang H. A review of the effects of collagen treatment in clinical studies. <em>Polymers (Basel)<\/em>. November 2021;13(22):3868.<\/li>\n<li>Collagen supplements market size, share &amp; trend analysis report by form (pills &amp; gummies, powder, liquid\/drinks), by distribution channel (pharmacy, online store, specialty store), by region, and segment forecasts, 2022-2028. Grand View Research. 2022.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Collagen is the most abundant protein in the human body, serving as the main structural protein of skin, tendons, ligaments, and bones. Although milk-based protein, specifically whey, dominates the global protein market, in part because it is inexpensive to manufacture &hellip; <a href=\"https:\/\/ulprospector.ul.com\/13898\/fb-collagen-benefits-types-and-market\/\">Continued<\/a><\/p>\n","protected":false},"author":60,"featured_media":13901,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","footnotes":""},"categories":[2],"tags":[],"ppma_author":[1282],"class_list":{"0":"post-13898","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-food-beverage-nutrition","8":"entry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Collagen: Benefits, Types, and Market - Prospector Knowledge Center<\/title>\n<meta name=\"description\" content=\"Collagen supplements are increasing in popularity. 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