{"id":19373,"date":"2025-06-11T06:00:01","date_gmt":"2025-06-11T12:00:01","guid":{"rendered":"https:\/\/www.ulprospector.com\/knowledge\/?p=19373"},"modified":"2025-05-15T08:58:36","modified_gmt":"2025-05-15T14:58:36","slug":"pe-wet-type-electrospinning-produces-cellulose-fibres-suited-for-biomedical-applications","status":"publish","type":"post","link":"https:\/\/ulprospector.ul.com\/19373\/pe-wet-type-electrospinning-produces-cellulose-fibres-suited-for-biomedical-applications\/","title":{"rendered":"Wet-type electrospinning produces cellulose fibres suited for biomedical applications"},"content":{"rendered":"

Textile, clothing, toys, sports equipment and other products made from synthetic petroleum-based materials have a significant negative impact on the environment through their entire life cycle, from production to waste management. It is important to replace petroleum-based materials with environmentally friendly materials and to re-use them wherever possible.<\/p>\n

Increased use of cellulose-based polymers<\/a> \u2013 derived from the primary plant scaffold and therefore a natural building block \u2013 could address many issues associated with petroleum-based polymers. Cellulose is the Earth\u2019s most abundant and widespread natural polysaccharide, commonly found in plant cell walls, algae or synthesised by certain bacteria.<\/p>\n

Now, scientists at the Faculty of Chemical Technology (CTF) at the Kaunas University of Technology (KTU) in Lithuania. have developed a production method for a nanofibrous cellulose matrix, which has the potential to replace non-renewable alternatives, even in biomedical applications<\/a>.<\/p>\n

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According to PhD student Ingrida Pauliukaityt\u0117, one of the creators of the new environmentally friendly cellulose nanofibre, products that have been in use for many years can be replaced while retaining their effectiveness. \u201cI chose cellulose because of its natural origin and favourable properties – its biocompatibility and degradability, variety of chemical strains, and potential in wide range of applications,\u201d said Pauliukaityt\u0117.<\/p>\n

\"Cellulose\"
Scanning electron microscope (SEM) image of new cellulose nanofibre.<\/figcaption><\/figure>\n

The process uses wet-type electrospinning, whereby cellulose is dissolved in special solvents \u2013 environmentally friendly ionic liquids \u2013 and the solution is then converted into fibres. \u201cThis is a method that allows the creation of cellulose matrices with a unique gel-like structure, similar to the cellulose fibres naturally synthesised by bacteria,\u201d Pauliukaityt\u0117 added.<\/p>\n

Importantly, the raw material for this production process can be either raw cellulose or cellulose waste. Depending on the purity of the material, the resulting fibre can be used for different products, including toys, sports equipment and household items. While if the raw material is pure plant cellulose, biomedical applications have great potential, where this type of nanofibrous structure has unique biocompatibility properties, very important in tissue engineering to avoid the living organism\u2019s immune response to a material used for cell reproduction other than the one naturally synthesised by the organism.<\/p>\n

\u201cOur invention \u2013 a nanofibrous cellulose matrix \u2013 is like a scaffold, a structural support that helps cells to divide and grow,\u201d explains Pauliukaityt\u0117. \u201cIn addition, cellulose has very favourable mechanical properties. The fibres developed are strong and can withstand the high stresses that arise when cells proliferate. Since cellulose absorbs water, the use of cellulose fibres in wound healing can control the amount of moisture is present during the healing process,\u201d says Pauliukaityt\u0117.<\/p>\n

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So far, cellulose in tissue engineering has been tested for the reconstruction of cartilage, bone and vascular structures. However, given the biocompatibility, structural and moisture retention properties of cellulose, this polymer has great potential for use in regenerative medicine, which aims to stimulate the body\u2019s natural recovery mechanisms and restore lost biological functions, and for organ growth.<\/p>\n

In addition, the cellulose nanofibres can also form three-dimensional (3D) cell models that better reflect cell behaviour in the natural environment. \u201cThis is a significant advantage, especially in tissue engineering and cancer research, as 3D cultures allow for more precise experiments and a better understanding of cell growth and interactions,\u201d said Pauliukaityt\u0117.<\/p>\n

Reference: Pauliukaityt\u0117, I. et al. (2024a) Regenerated nanofibrous cellulose electrospun from ionic liquid: Tuning properties toward tissue engineering. Journal of Biomedical Materials Research Part A. doi:10.1002\/jbm.a.37798.
\n<\/em>https:\/\/en.ktu.edu\/news\/lithuanian-scientists-develop-cellulose-recycling-method-with-applications-ranging-from-textiles-to-medical-devices\/<\/a><\/p>\n

 <\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Textile, clothing, toys, sports equipment and other products made from synthetic petroleum-based materials have a significant negative impact on the environment through their entire life cycle, from production to waste management. It is important to replace petroleum-based materials with environmentally … 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