{"id":8436,"date":"2018-07-06T08:00:51","date_gmt":"2018-07-06T14:00:51","guid":{"rendered":"https:\/\/www.ulprospector.com\/knowledge\/?p=8436"},"modified":"2018-07-13T11:35:31","modified_gmt":"2018-07-13T17:35:31","slug":"pcc-nanotechnology-in-cosmetics","status":"publish","type":"post","link":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/","title":{"rendered":"Downsizing: Nanotechnology in Cosmetics"},"content":{"rendered":"<figure id=\"attachment_8437\" class=\"thumbnail wp-caption alignright\" style=\"width: 600px\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-8437\" src=\"https:\/\/ulprospector.ul.com\/media\/2018\/07\/man-skincare-55590096_600x400.jpg\" alt=\"Man applying skin care product - learn how nanotechnology is being used in cosmetics in the Prospector Knowledge Center.\" width=\"600\" height=\"400\" srcset=\"https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2018\/07\/man-skincare-55590096_600x400.jpg 600w, https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2018\/07\/man-skincare-55590096_600x400-300x200.jpg 300w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><figcaption class=\"caption wp-caption-text\">Copyright: <a href=\"https:\/\/www.123rf.com\/profile_antoniodiaz\" target=\"_blank\" rel=\"noopener\">antoniodiaz \/ 123RF Stock Photo<\/a><\/figcaption><\/figure>\n<p>Nanotechnology in cosmetic products might not be considered a new technology, as liposomes were introduced to the market in the 1980\u2019s. Since then we\u2019ve seen the rise of several trends, including peptides, proteomics, stem cells and epigenetics. Howsoever, cosmetic companies including L\u2019Oreal, P&amp;G, Henkel, Unilever, Dior and Johnson &amp; Johnson publish several nanotechnology-related patents every year, which means that investments in this research area are relevant to this day.<\/p>\n<h3>What are cosmetic nanomaterials?<\/h3>\n<p>The EU Regulation 1223\/2009 defines the term \u2018nanomaterial\u2019 as an \u201cinsoluble or biopersistant and intentionally manufactured material with one or more external dimensions, or an internal structure, on the scale from 1 to 100 nm\u201d. Under this regulation, many biodegradable nanoparticle formulations used in cosmetic products are not considered nanomaterials and many suppliers are using this fact to name their ingredients \u2018submicron particles\u2019 instead of \u2018nanoparticles\u2019. Uncertainty and bias usually accompanies the surge of new technologies, which is the case with nanotechnology; many cosmetic companies are unclear in their communications about what technologies are used in their products.<\/p>\n<p>More importantly, one should be reminded that nanotechnology includes the \u201cunderstanding and control of matter and processes at the nanoscale, typically, <em>but not exclusively<\/em>, below 100 nanometres in one or more dimensions where the <em>onset of size-dependent phenomena<\/em> usually enables novel applications\u201d as defined by the ISO\/TC 229. Accordingly, submicron particles act as delivery systems and convey different properties to materials in that size range, hence they will be considered nanoparticles in the scope of this article.<\/p>\n<hr \/>\n<h3>Looking for nanomaterials for your personal care formulations?<\/h3>\n<p>UL Prospector\u00ae offers listings for more than 100 ingredients and formulations that capitalize on nanotechnology. View technical data, request samples, and contact global suppliers today!<\/p>\n<h3><a href=\"https:\/\/www.ulprospector.com\/en\/na\/PersonalCare\/search?k=nano&amp;st=31\" target=\"_blank\" rel=\"noopener\">Search nanomaterials\u00a0\u00a0<\/a><\/h3>\n<hr \/>\n<p>The size-dependent phenomena nanoparticles present are primarily linked to the higher surface area of particles in the nanoscale, which alter their optical properties (e.g. inorganic sunscreens will look transparent upon application on skin), and encapsulated fragrances can last longer and perform better. In addition, nanostructures can:<\/p>\n<ul>\n<li>Protect cosmetic actives from light or oxygen &#8211; especially advantageous for antioxidant molecules;<\/li>\n<li>Overcome insolubility problems;<\/li>\n<li>Control the release of substances;<\/li>\n<li>Perform better because of penetration into deeper skin layers through increase in skin permanence.<\/li>\n<\/ul>\n<p>Many substances have been incorporated into nanostructures to benefit from these properties, including retinoids, antioxidants (e.g. resveratrol and curcumin), sunscreens (e.g. benzophenone-4 and avobenzone), peptides, depigmenting agents, among others. Particles in the nanometric size range have also the ability to scatter UV light, thus acting as physical UV filters.<\/p>\n<p>In addition to these advantages, nanoparticles in general provide good hydration. This is due to an occlusion effect that is proportional to the decrease in size of nanoparticles and hence increase in particle number that form a protective thin film on the skin and reduce the trans-epidermal water loss (TEWL). Even though nanoparticles may be formed by solid or liquid lipids, the technology helps avoid the greasy appearance after application on the skin and the overall sensorial properties also improve.<\/p>\n<h3>Manufacturing nanocosmetics<\/h3>\n<p>The manufacture of a nanocosmetic requires some additional steps compared to other cosmetics. One must carefully analyse the need to incorporate an active substance into nanostructures and fully understand the purpose of encapsulation. Many suppliers of cosmetic ingredients produce nanotechnology-related formulations, ready to be incorporated into cosmetic bases. The advantage is that no internal development is needed, which requires specialized equipment and resources. Some examples of ingredients are listed below:<\/p>\n<ul>\n<li><a href=\"https:\/\/www.ulprospector.com\/en\/eu\/PersonalCare\/Detail\/17266\/427010\/NLT-AdenoSphere-20?st=31\" target=\"_blank\" rel=\"noopener\">NLT AdenoSphere 2.0<\/a> (liposomes with 2% adenosine) by BioSpectrum, Inc<\/li>\n<li><a href=\"https:\/\/www.ulprospector.com\/en\/eu\/PersonalCare\/Detail\/2249\/63513\/Nano-Lipobelle-H-EQ10?st=31\" target=\"_blank\" rel=\"noopener\">Nano-Lipobelle H-EQ10<\/a> (nanoemulsion with 5% coenzyme Q10 and 10% vitamin E acetate) by Mibelle AG Biochemistry<\/li>\n<li><a href=\"https:\/\/www.ulprospector.com\/en\/na\/PersonalCare\/Detail\/19322\/532201\/LPDs-Lightening-PF?st=31\" target=\"_blank\" rel=\"noopener\">LPD\u2019s Lightening<\/a> (liposomes with sodium ascorbyl phosphate) and <a href=\"https:\/\/www.ulprospector.com\/en\/eu\/PersonalCare\/Detail\/19323\/532224\/LPDs-Slimming?st=31\" target=\"_blank\" rel=\"noopener\">LPD\u2019s Slimming<\/a> (liposomes with caffeine, Ivy extract and Laminaria digitata extract) by Infinitec<\/li>\n<li>Crystalide (lipid nanoparticles containing tripeptide) by Sederma<\/li>\n<li>BergaCare SmartCrystals Rutin (nanocrystals of rutin) by Berg + Schmidt<\/li>\n<\/ul>\n<p>On the other hand, many companies choose to develop nanotechnology-based formulations internally to leverage the scientific knowledge of the company through patented formulations and exclusive products. See below for an overview of different types of nanoparticles that can be industrially produced.<\/p>\n<h3>Nanocrystals<\/h3>\n<p>The potential skin applications of plant-derived compounds such as astaxanthin, lutein, and curcumin is becoming well-known due to studies showing collagen and elastin production stimulation. The greatest issue with using these compounds in cosmetic formulations is their poor solubility in water and oil. In this way, nanocrystals of pure substances processed below 1000 nm (and stabilized by surfactants or polymers) solved this problem by increasing the saturation solubility of these compounds because of increased surface area of nanoparticles.<\/p>\n<p>Milling, high-pressure homogenisation (HPH) and controlled precipitation\/crystallization are common methods to produce nanocrystals in industrial scale.<\/p>\n<h3>Liposomes<\/h3>\n<p>Liposomes are composed of phospholipids such as phosphatidylcholine, phosphatidylserine, or phosphatidylethanolamine. Due to their amphipathic nature, they form bilayers in water that self-assemble into spherical vesicles with a hydrophilic core. Several methods are available to produce liposomes, and their size can be reduced with membrane extrusion techniques or HPH.<\/p>\n<p>The main advantage of liposomes is that hydrophilic and lipophilic substances can be incorporated into the aqueous core and into the lipid bilayer, respectively. In addition, phospholipids naturally occur in the skin and for this reason they are considered biocompatible, biodegradable and non-immunogenic.<\/p>\n<p>On the other hand, liposomes can be physically and chemically unstable, prone to aggregation and lipid peroxidation during storage.<\/p>\n<h3>Lipid nanoparticles<\/h3>\n<p>There are two generations of lipid nanoparticles: Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC). The first generation of lipid nanoparticles was made of solid lipids surrounded by an aqueous phase and stabilized by surfactants and\/or emulsifiers. The main drawback found for the first generation was the crystallization of the solid lipids and consequent expulsion of the active substances from the nanoparticle.<\/p>\n<p>This problem was overcome with the second generation of nanoparticles, in which the core is a mixture of solid and liquid lipids in varied proportions, hence keeping an amorphous structure and stabilizing the active substance within the nucleus.<\/p>\n<p>Lipid nanoparticles improve the penetration of cosmetic actives by slowly releasing to the skin from the reservoir. In addition, lipid nanoparticles have an occlusive effect, thus reducing the TEWL and help maintaining a proper level of hydration. They are also known for their UV scattering effect, acting synergistically with chemical sunscreens to increase the SPF in cosmetic products.<\/p>\n<p>The production of lipid nanoparticles requires high energy equipment to break down larger lipid droplets into nanoparticles. This is achieved with the use of HPH, available from laboratory to industrial scale. HPHs push a liquid formulation through a gap in the range of micrometres with high pressure (100 \u2013 2000 bar). The production of formulations using HPH is cost-effective and suitable for large-scale production, and many products using this technology can be found in the market.<\/p>\n<h3>Polymeric nanocapsules<\/h3>\n<p>Nanocapsules are core-shell structures in the nanometric range. The core can be liquid, semi-solid or solid and it\u2019s usually comprised of hydrophobic molecules. The shell is a polymeric membrane surrounding the core, typically made of polymers such as PCL, PLA, PLGA, PVP, among others. Natural polymers such as chitosan, sodium alginate, and albumin can also be used to formulate nanocapsules.<\/p>\n<p>Because the active substance is usually confined within the core of the nanocapsule, the polymeric wall acts as a barrier to diffusion, which helps avoid a burst release and achieve controlled release. This reduces any irritability the active may present and also improves the chemical stability of the active. Moreover, the external coating of nanocapsules can be modified with other molecules so properties like adhesivity to the skin can be achieved.<\/p>\n<p>One of the methods used to produce polymeric nanocapsules is nanoprecipitation. Industrial production can be achieved in different ways, based on the same principles of laboratory scale batches. The production involves solubilisation of the polymer and oil phase in an organic solvent, with consequent injection of that phase into an aqueous phase containing a surfactant \u2013 this is where the nanoprecipitation will occur. The organic solvent is removed through distillation. One can also perform spray-drying of the aqueous suspensions, and create a final powder formulation that is easily redispersed.<\/p>\n<h3>Other remarks<\/h3>\n<p>Nanotechnology-based formulations can provide great advantages to a cosmetic, but may pose some challenges during development. It is very important to consider the proper characterization of nanocosmetics as a fundamental step during development, since the stability and performance of the product will strongly relate to that. To develop a reliable, reproducible and effective product, it\u2019s best to analyse multiple parameters. Characterization techniques include average size and size distribution, polydispersity index, zeta potential, and morphology.<\/p>\n<h3>Further reading<\/h3>\n<ul>\n<li><a href=\"https:\/\/ulprospector.ul.com\/5760\/pcc-nanomaterials-eu-regulation-1223-2009-update?st=31\" target=\"_blank\" rel=\"noopener\">When Small is Big: Nanomaterials EU Regulation 1223\/2009 Update<\/a><\/li>\n<li><a href=\"https:\/\/ulprospector.ul.com\/2813\/pcc-news-brief-green-antimicrobial-nanoparticles-combine-lignin-silver?st=31\" target=\"_blank\" rel=\"noopener\">News Brief: \u201cGreen\u201d Antimicrobial Nanoparticles Combine Lignin &amp; Silver<\/a><\/li>\n<li><a href=\"https:\/\/ulprospector.ul.com\/764\/pcc-oil-water-emulsions?st=31\" target=\"_blank\" rel=\"noopener\">Oil in Water Nano-emulsions<\/a><\/li>\n<\/ul>\n<h3>References<\/h3>\n<p>Nanobiomaterials in Galenic Formulations and Cosmetics. DOI: http:\/\/dx.doi.org\/10.1016\/B978-0-323-42868-2.00001-2. Elsevier Inc. 2016.<\/p>\n<p>Nanocosmetics and Nanomedicines \u2013 New Approaches for Skin Care. DOI 10.1007\/978-3-642-19792-5. Springer 2011.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nanotechnology in cosmetic products might not be considered a new technology, as liposomes were introduced to the market in the 1980\u2019s. Since then we\u2019ve seen the rise of several trends, including peptides, proteomics, stem cells and epigenetics. Howsoever, cosmetic companies &hellip; <a href=\"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/\">Continued<\/a><\/p>\n","protected":false},"author":71,"featured_media":8437,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","footnotes":""},"categories":[5],"tags":[247],"ppma_author":[1287],"class_list":{"0":"post-8436","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-personal-care-cosmetics-cleaners","8":"tag-application","9":"entry"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Downsizing: Nanotechnology in Cosmetics - Prospector Knowledge Center<\/title>\n<meta name=\"description\" content=\"What are cosmetic nanomaterials? Find out what to consider when manufacturing a nanocosmetic, and different types of nanoparticles that can be produced.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Downsizing: Nanotechnology in Cosmetics - Prospector Knowledge Center\" \/>\n<meta property=\"og:description\" content=\"What are cosmetic nanomaterials? Find out what to consider when manufacturing a nanocosmetic, and different types of nanoparticles that can be produced.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/\" \/>\n<meta property=\"og:site_name\" content=\"Prospector Knowledge Center\" \/>\n<meta property=\"article:published_time\" content=\"2018-07-06T14:00:51+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2018-07-13T17:35:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2018\/07\/man-skincare-55590096_800x420.png\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"420\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Gabriele Dadalt Souto\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/ulprospector.ul.com\/media\/2018\/07\/man-skincare-55590096_600x400-150x150.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Gabriele Dadalt Souto\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/\"},\"author\":{\"name\":\"Gabriele Dadalt Souto\",\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/#\\\/schema\\\/person\\\/33044526d6f7718d6e64946858a50395\"},\"headline\":\"Downsizing: Nanotechnology in Cosmetics\",\"datePublished\":\"2018-07-06T14:00:51+00:00\",\"dateModified\":\"2018-07-13T17:35:31+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/\"},\"wordCount\":1483,\"commentCount\":1,\"image\":{\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ulprospector.ul.com\\\/wp-content\\\/uploads\\\/2018\\\/07\\\/man-skincare-55590096_600x400.jpg\",\"keywords\":[\"Application\"],\"articleSection\":[\"Personal Care &amp; Cosmetics\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/\",\"url\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/\",\"name\":\"Downsizing: Nanotechnology in Cosmetics - Prospector Knowledge Center\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/ulprospector.ul.com\\\/wp-content\\\/uploads\\\/2018\\\/07\\\/man-skincare-55590096_600x400.jpg\",\"datePublished\":\"2018-07-06T14:00:51+00:00\",\"dateModified\":\"2018-07-13T17:35:31+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/#\\\/schema\\\/person\\\/33044526d6f7718d6e64946858a50395\"},\"description\":\"What are cosmetic nanomaterials? Find out what to consider when manufacturing a nanocosmetic, and different types of nanoparticles that can be produced.\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/#primaryimage\",\"url\":\"https:\\\/\\\/ulprospector.ul.com\\\/wp-content\\\/uploads\\\/2018\\\/07\\\/man-skincare-55590096_600x400.jpg\",\"contentUrl\":\"https:\\\/\\\/ulprospector.ul.com\\\/wp-content\\\/uploads\\\/2018\\\/07\\\/man-skincare-55590096_600x400.jpg\",\"width\":600,\"height\":400,\"caption\":\"Copyright: antoniodiaz \\\/ 123RF Stock Photo\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/8436\\\/pcc-nanotechnology-in-cosmetics\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/ulprospector.ul.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Downsizing: Nanotechnology in Cosmetics\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/#website\",\"url\":\"https:\\\/\\\/ulprospector.ul.com\\\/\",\"name\":\"Prospector Knowledge Center\",\"description\":\"Welcome to the blog for UL Prospector, the most comprehensive raw material search engine for product developers.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/ulprospector.ul.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/#\\\/schema\\\/person\\\/33044526d6f7718d6e64946858a50395\",\"name\":\"Gabriele Dadalt Souto\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/ulprospector.ul.com\\\/media\\\/2018\\\/05\\\/Gabriele-Dadalt-Souto_avatar_1525206849-96x96.jpgfceb9272cf8d1ca40f3a50ef98154186\",\"url\":\"https:\\\/\\\/ulprospector.ul.com\\\/media\\\/2018\\\/05\\\/Gabriele-Dadalt-Souto_avatar_1525206849-96x96.jpg\",\"contentUrl\":\"https:\\\/\\\/ulprospector.ul.com\\\/media\\\/2018\\\/05\\\/Gabriele-Dadalt-Souto_avatar_1525206849-96x96.jpg\",\"caption\":\"Gabriele Dadalt Souto\"},\"description\":\"Gabriele Dadalt Souto is a Senior Formulation Chemist in Oriflame R&amp;D, a Swedish beauty company selling direct, working in the Personal and Hair Care new product development. Oriflame is present in more than 60 countries, offering a wide range of high-quality beauty products committed to the principles of sustainability. Gabriele received her Ph.D. in Pharmaceutical Nanotechnology from the Federal University of Rio Grande do Sul (Brazil) in 2014, completed post-doctorates in Ireland and Brazil, and worked for L\u2019Oreal India before joining Oriflame. She is a member of the Society of Cosmetic Scientists (SCS). Her expertise lies in formulation science and technology ranging from liposomes, lipid, and polymeric nanoparticles to emulsions, surfactants, and a wide range of skin, personal and hair care formulations. In addition, Gabriele has experience in Marketing Strategy, Consumer Science, Quality Assurance and Research &amp; Development of innovative cosmetic products, having authored a patent while working in L\u2019Oreal. She has published numerous scientific articles and trained several graduate students on scientific project management and methodology development.\",\"url\":\"https:\\\/\\\/ulprospector.ul.com\\\/author\\\/gabriele\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Downsizing: Nanotechnology in Cosmetics - Prospector Knowledge Center","description":"What are cosmetic nanomaterials? Find out what to consider when manufacturing a nanocosmetic, and different types of nanoparticles that can be produced.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/","og_locale":"en_US","og_type":"article","og_title":"Downsizing: Nanotechnology in Cosmetics - Prospector Knowledge Center","og_description":"What are cosmetic nanomaterials? Find out what to consider when manufacturing a nanocosmetic, and different types of nanoparticles that can be produced.","og_url":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/","og_site_name":"Prospector Knowledge Center","article_published_time":"2018-07-06T14:00:51+00:00","article_modified_time":"2018-07-13T17:35:31+00:00","og_image":[{"width":800,"height":420,"url":"https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2018\/07\/man-skincare-55590096_800x420.png","type":"image\/png"}],"author":"Gabriele Dadalt Souto","twitter_card":"summary_large_image","twitter_image":"https:\/\/ulprospector.ul.com\/media\/2018\/07\/man-skincare-55590096_600x400-150x150.jpg","twitter_misc":{"Written by":"Gabriele Dadalt Souto","Est. reading time":"7 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/#article","isPartOf":{"@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/"},"author":{"name":"Gabriele Dadalt Souto","@id":"https:\/\/ulprospector.ul.com\/#\/schema\/person\/33044526d6f7718d6e64946858a50395"},"headline":"Downsizing: Nanotechnology in Cosmetics","datePublished":"2018-07-06T14:00:51+00:00","dateModified":"2018-07-13T17:35:31+00:00","mainEntityOfPage":{"@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/"},"wordCount":1483,"commentCount":1,"image":{"@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/#primaryimage"},"thumbnailUrl":"https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2018\/07\/man-skincare-55590096_600x400.jpg","keywords":["Application"],"articleSection":["Personal Care &amp; Cosmetics"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/","url":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/","name":"Downsizing: Nanotechnology in Cosmetics - Prospector Knowledge Center","isPartOf":{"@id":"https:\/\/ulprospector.ul.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/#primaryimage"},"image":{"@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/#primaryimage"},"thumbnailUrl":"https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2018\/07\/man-skincare-55590096_600x400.jpg","datePublished":"2018-07-06T14:00:51+00:00","dateModified":"2018-07-13T17:35:31+00:00","author":{"@id":"https:\/\/ulprospector.ul.com\/#\/schema\/person\/33044526d6f7718d6e64946858a50395"},"description":"What are cosmetic nanomaterials? Find out what to consider when manufacturing a nanocosmetic, and different types of nanoparticles that can be produced.","breadcrumb":{"@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/#primaryimage","url":"https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2018\/07\/man-skincare-55590096_600x400.jpg","contentUrl":"https:\/\/ulprospector.ul.com\/wp-content\/uploads\/2018\/07\/man-skincare-55590096_600x400.jpg","width":600,"height":400,"caption":"Copyright: antoniodiaz \/ 123RF Stock Photo"},{"@type":"BreadcrumbList","@id":"https:\/\/ulprospector.ul.com\/8436\/pcc-nanotechnology-in-cosmetics\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/ulprospector.ul.com\/"},{"@type":"ListItem","position":2,"name":"Downsizing: Nanotechnology in Cosmetics"}]},{"@type":"WebSite","@id":"https:\/\/ulprospector.ul.com\/#website","url":"https:\/\/ulprospector.ul.com\/","name":"Prospector Knowledge Center","description":"Welcome to the blog for UL Prospector, the most comprehensive raw material search engine for product developers.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/ulprospector.ul.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/ulprospector.ul.com\/#\/schema\/person\/33044526d6f7718d6e64946858a50395","name":"Gabriele Dadalt Souto","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/ulprospector.ul.com\/media\/2018\/05\/Gabriele-Dadalt-Souto_avatar_1525206849-96x96.jpgfceb9272cf8d1ca40f3a50ef98154186","url":"https:\/\/ulprospector.ul.com\/media\/2018\/05\/Gabriele-Dadalt-Souto_avatar_1525206849-96x96.jpg","contentUrl":"https:\/\/ulprospector.ul.com\/media\/2018\/05\/Gabriele-Dadalt-Souto_avatar_1525206849-96x96.jpg","caption":"Gabriele Dadalt Souto"},"description":"Gabriele Dadalt Souto is a Senior Formulation Chemist in Oriflame R&amp;D, a Swedish beauty company selling direct, working in the Personal and Hair Care new product development. Oriflame is present in more than 60 countries, offering a wide range of high-quality beauty products committed to the principles of sustainability. Gabriele received her Ph.D. in Pharmaceutical Nanotechnology from the Federal University of Rio Grande do Sul (Brazil) in 2014, completed post-doctorates in Ireland and Brazil, and worked for L\u2019Oreal India before joining Oriflame. She is a member of the Society of Cosmetic Scientists (SCS). Her expertise lies in formulation science and technology ranging from liposomes, lipid, and polymeric nanoparticles to emulsions, surfactants, and a wide range of skin, personal and hair care formulations. In addition, Gabriele has experience in Marketing Strategy, Consumer Science, Quality Assurance and Research &amp; Development of innovative cosmetic products, having authored a patent while working in L\u2019Oreal. She has published numerous scientific articles and trained several graduate students on scientific project management and methodology development.","url":"https:\/\/ulprospector.ul.com\/author\/gabriele\/"}]}},"authors":[{"term_id":1287,"user_id":71,"is_guest":0,"slug":"gabriele","display_name":"Gabriele Dadalt Souto","avatar_url":"https:\/\/ulprospector.ul.com\/media\/2018\/05\/Gabriele-Dadalt-Souto_avatar_1525206849-96x96.jpg","0":null,"1":"","2":"","3":"","4":"","5":"","6":"","7":"","8":""}],"_links":{"self":[{"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/posts\/8436","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/users\/71"}],"replies":[{"embeddable":true,"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/comments?post=8436"}],"version-history":[{"count":0,"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/posts\/8436\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/media\/8437"}],"wp:attachment":[{"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/media?parent=8436"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/categories?post=8436"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/tags?post=8436"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/ulprospector.ul.com\/wp-json\/wp\/v2\/ppma_author?post=8436"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}